Bone matrix to growth factors: location, location, location
نویسندگان
چکیده
The demonstration that fibrillin-1 mutations perturb transforming growth factor (TGF)-β bioavailability/signaling in Marfan syndrome (MFS) changed the view of the extracellular matrix as a passive structural support to a dynamic modulator of cell behavior. In this issue, Nistala et al. (2010. J. Cell Biol. doi: 10.1083/jcb.201003089) advance this concept by demonstrating how fibrillin-1 and -2 regulate TGF-β and bone morphogenetic protein (BMP) action during osteoblast maturation.
منابع مشابه
A Review of Spatial Factor Modeling Techniques in Recommending Point of Interest Using Location-based Social Network Information
The rapid growth of mobile phone technology and its combination with various technologies like GPS has added location context to social networks and has led to the formation of location-based social networks. In social networking sites, recommender systems are used to recommend points of interest (POIs) to users. Traditional recommender systems, such as film and book recommendations, have a lon...
متن کاملA Multi-Criteria Decision Making for Location Selection in the Niger Delta Using Fuzzy TOPSIS Approach
Making an informed decision with regards to a suitable business location or site selection for organizations is becoming challenging for business decision makers globally; and even more challenging in business environment that are saddled with uncertainties. The continues raise of multiple criteria variation of site preferences has also necessitated the application of advanced decision making t...
متن کاملLogical selection of potential hub nodes in location of strategic facilities by a hybrid methodology of Data Envelopment Analysis and Analytic Hierarchical Process: Iran Aviation case study
Hub facility location problem looks to find the most appropriate location for deploying such facilities. An important factor in such a problem is the pool of potential locations from which the optimal locations must be selected. The present research was performed to address two key objectives: identifying the factors contributing to the selection locations for hub establishment, and presenting ...
متن کاملSerum Factors Induced the Nuclear Location of Annexin V in the Human Osteosarcoma Cell Line (MG-63)
Calcium-binding proteins play essential roles in the cell. One important class of calcium-binding proteins is the annexin family. This is a family of 13 proteins, which binds to phospholipids in a calcium-dependent manner. Osteosarcoma cell line (MG-63) is a transformed cell that has many characteristics of the differentiated cell, such as a considerable serum dependency in its growth rate. Usi...
متن کاملFactors influencing the location of landuses in the Rural Projects
Locational analysis of landuse is being considered as relatively final step regarding landuse Planning. It is being argued that the locational analysis is being influenced by many varied factors. However, optimum location is associated with great accessibility. This study tries to identify major factors responsible for proposed rural settlements guiding plan in Iran. Different involved criteria...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 190 شماره
صفحات -
تاریخ انتشار 2010